Archive for February 2020

Epispadias: What You Should Know

Epispadias is a rare urological condition that is present at birth. The urinary tract is affected and the way that urine exits the body is altered.

Both boys and girls can be born with Epispadias. However, boys are affected more often than girls. There are many types of Epispadias Repair Surgery to fix the problem.

The urinary tract has two kidneys, two ureters, the urethra and bladder. The kidneys filter out toxins, but keep salts, sugar, proteins and minerals. The waste product is known as urine. It’s made in the kidneys, goes down two tubes called ureters and is pushed into the bladder. The path closes so the urine can’t flow back to the kidneys. When it’s time to release urine out of the body, it’s carried from the bladder by a tube called the urethra.

How It Affects Boys

Epispadias affects 1 in 117,000 boys. Normally, the urethra opening is at the tip of the penis. With Epispadias, it’s on top of the penis.

There are 3 types of Epispadias in boys. It’s classified based on the location of the urethra on the penis.

  • Glandular Epispadias – on the head of the penis
  • Penile Epispadias – along the shaft of the penis
  • Penopubic Epispadias – near the pubic bone

Depending on the position of the urethra, it predicts how well the urine is stored in the bladder. If it’s close to the abdominal wall, base of the penis, it probably won’t hold urine because the bladder sphincter is affected.

How It Affects Girls

Epispadias affects 1 in 484,000 girls, so it’s very rare.

When the baby girl is born, the pubic bones are separated into two different degrees, making the clitoris split down the middle. The bladder neck is usually affected.

When she coughs or with strenuous effort, she is likely to leak urine.

Before Epispadias Repair Surgery

After a diagnosis of Epispadias, tests are done to check the urinary tract, colon, pelvis and abdomen for other defects. With these tests, the nature of the problem is determined and a surgical treatment course is dictated.

If areas, such as the bladder are exposed, when it’s usually covered by skin, the procedure to close it up is usually performed while the child is still a newborn.

Due to the wide variety of issues that can be present with Epispadias, the treatment plan is unique with each child.

Treatment Options For Boys

The treatment goals are:

  • Fix penis bends
  • Make the penis look normal
  • Make the penis a good length
  • Make sure the penis works
  • If the bladder and it’s neck are affected, surgery will be needed so the child can control the urine
  • To preserve fertility, surgery might be needed

There are two Epispadias Repair Surgeries that can be done on boys, Mitchell Technique and Modified Cantwell Technique.

If Mitchell Technique is done, the surgeon will completely take the penis apart and put it back together. He makes sure that the dorsal band is connected and the urethra is in the most normal and functional position.

The Modified Cantwell Technique is used to rebuild the penis. Some of the penis is taken apart to move the urethra to a better position.

Treatment Options For Girls

If the baby girl is diagnosed at birth, the clitoris can be brought together and the urethra can be put in its normal position. Lack of urinary control might not happen.

The girls reconstruction is less complex than boys. The ovaries, Fallopian tubes and uterus are usually normal.

Typically, patients undergoing Epispadias Repair Surgery recovers very quickly.

Automated Liquid Handling Guide

People seldom give much thought to liquids. Or rather they seldom stop to think about the distinct qualities liquids have which differentiate them from other forms of matter. But all of that changes rather quickly when those liquids are part of a medical setting. Liquids in medical settings tend to have some powerful properties. The end result is that they’re also often difficult to directly handle. This is why automated liquid handling is so important. But at the same time, one needs to use some care and consideration when using these systems.

One should begin by thoroughly understanding the typical volume one will work with. There’s several reasons why this is important. One of the most readily apparent is that volume necessitates the type of containers used. It can also determine which automated system to use.

However, volume also impacts which system will be the optimal choice for particular environments. An environment which only works with solutions in a range from one to five ML can standardize on a particular workflow fairly easily. However, consider the case of jobs which require moving between 1 ML and 20 ML batches. This can impact why someone would want to go with higher tech models such as a Hamilton Nimbus. The Hamilton Nimbus would make it easier for people to work with such a highly variable system.

Next, one should also consider end needs. Again, it’s important to keep a steady workflow in mind. People often assume that their needs will remain unchanging. But one will usually do himself a favor by considering needs five or six years into the future. And this is particularly true when it comes to automated liquid handling systems.

It’s quite common for people to upgrade these systems. And it generally means turning them into a full workstation. These are more modular setups which use the liquid handling as one part of a greater whole. However, some people also try to go with a one size fits all solution right from the start.

It’s usually best to plan for a modular upgrade cycle in the future. One doesn’t have to fully anticipate demands. And in many ways it’s often not even possible to guess what one’s needs will be in the distant future. But one can at least consider whether upgrades will be called for at all. If so, one should try to design around a modular upgrade cycle. This will make the upgrades go far more smoothly in the future.

One should also consider the nature of liquids one will deal with. This will impact both the choice of system and the containers used with it. The most pressing concern is usually overall viscosity of the liquid. Consider just how different water is from oil. It’s not just a matter of solubility of other elements within the liquid. One must also contend with difficulties in fully transferring those liquids between separate containers. This will also influence pipette choice.

Additionally, the pipettes themselves need to be considered as well. One should consider what would happen to a sample if tip ejection is compromised. And with many types of pipette it’s true that aggressive loading makes for difficult ejection. Choice of pipette can influence the severity of this reaction. Some types will even eliminate the concern. However, as with most parts of an automated system one needs to plan for it.

Planning is the final consideration which needs to go into any automated liquid handling design. The modular nature of these systems does mean that one can often modify plans on the fly. But one should try to minimize variables in overall design just as one would during an experimental procedure.

Top Reasons to Prefer Temp Workers for General Labor Jobs Toronto

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So, after a tiring summer season, it’s finally fall and probably would be the busiest of all seasons for many employers. At this time, it’s not only about having a heavy workload but, it also involves a lot of efforts from the hiring managers. Some companies might be ramping up their production to enjoy the upcoming holiday season to the fullest while others would try hard to achieve their quarterly targets.

Whatever be the prevailing conditions, it’s obvious to see most of the summer temp employees leaving the jobs or better and permanent positions. Here, what most of the companies do not realize is the importance of having these temp workers who are already quite aware about the company and relevant general labor jobs Toronto. Since a professional and dedicated employer understands the significance of having such workers, they used to plan something to sustain those temporary workers in one way the other. If someone doesn’t know the reasons behind it, here is why they should be more concerned from now:

  • Fewer Hires

As mentioned above, fall is the busiest season of the year when hiring is at its peak. Hiring managers and employers have to do extra efforts to meet their projects’ requirements. They have to focus on all areas of the work, be it production, marketing, sales, merchandising etc. Yes, they can also take help from employment agencies who have approach to a wide range of workforce as compared to what they can do on their own. Though, if an employer is satisfied with summer temp employees, then it’s ideal to extend their work tenure as soon as the existing one ends. 

  • No Need of Training

Since summer employees have been working for quite some time, employers do not have to invest more time on their training. The best part is that there won’t be any compromise on productivity since the company always have workers to get the jobs done. 

  • Temporary Workers also Want to Stay

Last but not the least, there are a few summer employees who also want to stay with the existing employer. With good experience and satisfaction by their side, they don’t want to switch their jobs. Sometimes, they are happy with the payout of general labor jobs Toronto because it is better than what other companies used to offer. 

  • Negotiation is Easy

Since summer employees are satisfied with the quality of services offered by the employer, they would agree to certain terms just to stay in the company for a long time period. This way, they are rest assured.

All in all, the decision to sustain summer employees is one of the best approaches because of the reliability and credibility of doing the jobs. The workers have better understanding about the work ethics and organizational environment, which allow them to maintain their productivity irrespective of the season and type of project they are working on. However, if someone needs assistance, it’s better to search for a reputed recruitment agency that possesses knowledge about each and every aspect.

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